Most exciting are the potential implications of this technology. SpaceOAR, a name that stands for Spacing Organs at Risk, was cleared by the US Food and Drug Administration (FDA) for use as an absorbable perirectal spacer.. How does SpaceOAR work? How to cite: Finklestein, Steven E. “Emerging Indications for a Novel Absorbable Hydrogel Spacer: A 2018 Review” November 9, 2018. Learn why Dr. Mehta and Mike opted to use SpaceOAR Hydrogel to minimize side effects of radiation treatment. Hypofractionated radiation therapy is standard of care for treating prostate cancer. The prostate and the rectum are situated right next to each other. The SpaceOAR system is a medical device developed by Augmenix to protect against rectal injury during radiation therapy for prostate cancer. Note: Thanks to Daniel Hamstra for allowing me to read the full text, and responding to my questions. Timing and Optimization of Radium 223 in CRPC, Perspectives in Urology: Point-Counterpoint, Prostate Health Podcast with Garrett D. Pohlman, MD, 27th Annual Perspectives in Urology: Point Counterpoint, Role of Brachytherapy in High-Risk Prostate Cancer, Next Generation Updates in Radiation Oncology, Update on Radiopharmaceuticals— Choosing a Companion Drug to Radium-223, Perspectives in Urology: Point Counterpoint. All rights reserved. IMRT has not done it. He reviews the clinical investigations of adjacent prostate indications, as well as indications in other organs throughout the body, for this technology. Due to proximity to the prostate, delivering a radiation dose to the rectum or the organ at risk (OAR). The ongoing, study investigates the sexual QOL of patients undergoing ultra-hypofractionation therapies.

Most exciting are the potential implications of this technology. No other randomized trial has identified such an improvement in erectile dysfunction and sexual QOL. Hypofractionated radiation therapy is standard of care for treating prostate cancer. supplements. Also, a study from the Medical University of South Carolina described how SpaceOAR can aid prostatic cryoablation. Delivered by ProstateCancerNewsReviews&Views, SpaceOAR hydrogel is spacer injected between the rectum and the prostate that increases their separation. This allows less radiation targeted at the prostate to hit the rectum. So to spare one patient those symptoms, 6 patients would have to be treated at a cost of $15,000. Due to proximity to the prostate, delivering a radiation dose to the rectum or the organ at risk (OAR) is inevitable unless prevented. SpaceOAR hydrogel is spacer injected between the rectum and the prostate that increases their separation. If you go back to the original Dutch 3D conformal trial published 15 years ago they showed reduced toxicity with 3D conformal RT as compared to 2D RT (but did not collect QOL). Mike chose to move forward with radiation therapy to treat his prostate cancer with the help of Dr. Mehta, from UroPartners, Glenview. ©2020 Boston Scientific Corporation or its affiliates. have published their final report based on … All trademarks are the property of their respective owners. Please talk with your doctor about the risks and benefits associated with the SpaceOAR. URO-709404-AA FEB 2020. Even if the difference were statistically significant (and it's not), only 2.2% would avoid bothersome late-term rectal symptoms by using the gel.

However, at high doses, it results in gastrointestinal tract side effects. Steven E. Finkelstein, MD, FACRO, is a radiation oncologist with Florida Cancer Affiliates in Panama City, Florida. © 2020 Boston Scientific Corporation or its affiliates. No other randomized trial has identified such an improvement in erectile dysfunction and sexual QOL. Perspectives in Urology: Point Counterpoint (PCP) is an annual CME-accredited conference devoted to discussing and debating the latest topics in men’s health, general urology, and genitourinary cancers. He is a member of the American College of Radiation Oncology, the American Medical Association, the American Society of Clinical Oncology, the American Society for Therapeutic Radiology and Oncology, the Radiological Society of North America, and the Radiation Therapy Oncology Group. "I think this is better than any other study ever performed for prostate cancer. Pierre, an 81-year-old from Texas was a former state champion in judo from age 64-66. Hear from him and his medical team, Dr. Sigman and Dr. Brookland, about how they determined the best treatment for Dr. Siegel, which included hormone and radiation therapy along with SpaceOAR Hydrogel. The SpaceOAR Hydrogel is composed of biodegradable material and maintains space for the entire course of prostate cancer radiotherapy treatment. All rights reserved. *American Cancer Society. Please check availability with your local sales representative or customer service. So to spare one patient bothersome rectal symptoms, 45 patients would have to be treated at a cost of over $90,000. I know of no phase 3 trials testing a new technique or study which randomized patients and reported benefits for toxicity and QOL. Currently, three studies are researching the effect of SpaceOAR with salvage post-prostatectomy. Dr. Finkelstein has also served as National Director of Translational Research Consortium (TRC), the cutting-edge therapy arm of 21st Century Oncology in Scottsdale, Arizona. After monitoring PSA levels for years, Alan was eventually diagnosed with prostate cancer. BSC strongly recommends that you consult with your physician on all matters pertaining to your Boston Scientific is dedicated to transforming lives through innovative medical solutions that improve the health of patients globally. Indications, contraindications, warnings and instructions for use can be found in the product labelling supplied with each device. When Henry was diagnosed with prostate cancer, his greatest fear was a diminishment of any aspect of his life. Posted by Steven E. Finkelstein, MD, FACRO | Jun 2019. Nor has any surgical technique. Currently, three studies are researching the effect of SpaceOAR with, study from the Medical University of South Carolina. Caution: The law restricts these devices to sale by or on the order of a physician. Current clinical trials, such as the NRG GU 005 and COMPPARE trials, allow the use of SpaceOAR in the same way as a rectal balloon. He currently serves on the Board of Chancellors for ACRO. A pivotal definitive external beam radiation therapy (EBRT) study, demonstrated that using SpaceOAR resulted in 74% less rectal radiation, 75% less late rectal toxicity, a creation of a 1.3 cm space, as well as long-term quality of life (QOL) benefits. He has served as a Co-Chair on the NRG Immunotherapy Committee, Co-Chair of the 2018-2019 ACRO Scientific Program Committee, and Chair of the SWOG Radiation STG Committee. Neoadjuvant/Adjuvant Chemotherapy: Are We Ready to Accept NAC as the Gold Standard? He writes a regular column for the New Prostate Cancer Infolink, and works with support groups.



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