According to French and German mythology, the nymph Ondine/Undine discovered that her husband had committed adultery.

Can you imagine how it would be if your body just forgot to breathe? In the 1993 video game Secret of Mana, Undine is the first spirit the player encounters.

But I have no idea whether that had anything to do with it or not. 66.1. According to legend, the water nymph Ondine cursed a man who promised that every waking breath he took would be a testament to his love, and then cheated on her. Supplemental oxygen must be provided cautiously to these patients, as oxygen administration can occasionally precipitate severe acute respiratory acidosis, leading to decreased ventilation and a further increase in PaCO2. The polysomnograph was applied to the investigation of patients with insomnia following the discovery of obstructive sleep apnea in 1965, and objective measures of hypnotic effectiveness were developed by Kales et al.

Patients are offered genetic counseling given the autosomal dominant pattern of inheritance and encouraged to avoid respiratory depressants such as opiates. They often have difficulty swallowing, for example, and can be susceptible to brain tumors as well.

Because he had promised his every waking breath to her, she cursed him that so long as he was awake he could breathe, but if he ever fell asleep he would stop breathing and die. Ondine's curse cannot be cured, but it can be managed and treated.

Ages 36 and 59 years, they had bilateral infarctions limited to the lateral medullary tegmentum. However, central nervous system (CNS) and brainstem-related nocturnal respiratory abnormalities such as paroxysmal hyperventilation, hypoventilation, respiratory muscle weakness, and respiratory arrest have all been described (Howard et al., 1992; Auer et al., 1996). The other bad part is that it can cause other problems like mild retardation, learning disabilities, speech problems and so forth because the child is not getting enough oxygen to the brain. In such patients, it is important to diagnose and promptly treat ventilatory dysfunction during sleep. As Ondine’s physical attractiveness diminished, Lawrence lost interest in his wife. Ever since she began contributing to the site several years ago, Mary has embraced the

Other mechanisms that may explain the detrimental effect of supplemental oxygen include (1) the Haldane effect, which refers to the reduction in hemoglobin affinity for CO2 with the binding of O2 to hemoglobin; (2) increase in oxygen tension in lung units with low ventilation/perfusion (V/Q) ratios, leading to increased dead space by stripping perfusion from high V/Q units; (3) diminished sensitivity of the central nervous system during hyperoxia; (4) increased susceptibility to the development of severe hypercapnia due to sleep deprivation, leading to sleep onset with associated loss of the wakefulness drive to breathe; and (5) reduction in minute ventilation, leading to increased fractional oxygen concentration from a noninvasive oxygen source, which then leads to worsening hypercapnia. In one of these patients the carbon dioxide response was markedly depressed. Debussy, Sibelius, Fauré, and Schoenberg all wrote music adaptions of the play.

[11], The offspring of a union between an undine and a man are human with a soul, but also with some kind of aquatic characteristic, called a watermark. Ondine's curse is now a medical term applied to a rare syndrome where the autonomic (involuntary) control of breathing is lost, resulting in the need to initiate every breath consciously. On meeting Ondine again on the day of his wedding to Bertha, Hans tells her that "all the things my body once did by itself, it does now only by special order ... A single moment of inattention and I forget to breathe". Charles Sidney Burwell in 1956 brought general recognition to obstructive sleep apnea syndrome, which he called the “pickwickian syndrome” (Burwell et al., 1956), and the first objective documentation of polysomnographic features was simultaneously reported by Henri Gastaut and Jung in 1965 (Gastaut et al., 1965; Jung and Kuhlo, 1965). We had a little girl who had ventilation problems from birth who was diagnised with Ondine's curse at our NICU. Nevertheless, recent studies have shown very low hospital mortality, which is probably related to improved care for respiration, infection and dysphagia.31. In general, severe hypercapnia from oxygen administration occurs during acute exacerbations of COPD among obese patients who likely have both acute and chronic sleep disturbances (from sleep apnea).

Furthermore, arousal responses and dyspneic sensation during hypercapnia and/or hypoxia are also absent. They are usually found in forest pools and waterfalls.

Ondine's curse [on´dēnz] a condition in which patients have lost autonomic control of respiration and become apneic upon falling asleep; it is due to lesions or surgery of the high spinal cord or brainstem; named after Ondine, a water nymph in Greek mythology who caused a mortal who loved her to sleep forever. Consistent with increased respiratory activity during REM sleep, breathing stability typically improves somewhat in this sleep state.

Ventilation will help the patient to breathe, and patients may also benefit from physical therapy and other supportive care which is designed to promote independence. This condition is also known as primary alveolar hypoventilation or congenital central hypoventilation syndrome (CCHS). The behavioral technique “stimulus control” developed by Richard Bootzin in 1972 was an effective treatment of insomnia, as was “sleep restriction therapy,” developed by Arthur Spielman in 1987 (Spielman et al., 1987). Ondine was a water nymph in German mythology. It is tempting to speculate that the variable autonomic nervous system (ANS) dysfunction in the extended families of patients with congenital CCHS is related to the presence of a “premutation” sized PHOX2B expansion (>20 and <24) with potential implications for diffuse ANS symptoms in the general population.

In 18th century Scotland, Undines were also referred to as the wraiths of water. Respiratory rate and pattern were studied by Lee and colleagues19 by impedance pneumography in 14 patients with acute brain stem or cerebral infarction, and in a subsequent study they reported on another 23 patients with acute brain stem infarction.21 They found frequent abnormalities of respiratory pattern and rate in such patients, and these abnormalities became worse during sleep.

The hospital mortality ranges from 0.8% to 11.6%.31,144–146 Patients with large, rostral lesions tend to have severe dysphagia, aspiration pneumonia, requiring ICU care. [5], Paracelsus believed that each of the four classical elements – earth, water, air and fire – is inhabited by different categories of elemental spirits, liminal creatures that share our world: gnomes, undines, sylphs and salamanders respectively. The name, Ondine's curse, is based upon a mythical mermaid named Ondine, the daughter of Poseidon, god of the sea.

Sleep disturbances have been described in brain stem infarction by Markand and Dyken275 and several other authors.19,21,276,277 Polysomnographic findings generally consisted of increased wakefulness after sleep onset and decreased REM and slow-wave sleep. The Association of Sleep Disorder Centers classification committee, chaired by Howard Roffwarg, produced the Diagnostic Classification of Sleep and Arousal Disorders in 1979; it ushered in the modern era of sleep diagnoses and became the first classification to be widely used.

Most cases present in the newborn period, although it is becoming increasingly recognized that milder cases can present at other times including into adulthood.

Congenital central hypoventilation syndrome (once known as ‘Ondine's curse’) is a somewhat rare condition characterized by marked alveolar hypoventilation which worsens significantly during sleep, resulting in major blood gas disturbances. In addition to those mentioned, a few of the many who have contributed to this recognition include: Roger Broughton, Michel Billiard, Christian Guilleminault, Peter Hauri, J. David Parkes, the late Pierre Passouant, and Bedrich Roth. Bogousslavsky et al.288 reported a clinical pathologic correlation in two patients who had central hypoventilation and unilateral infarct in the caudal brain stem. That's just the more common name but it's not really used so much in the medical field. The authors suggested that the aberrant vertebral artery might have compressed the respiratory center, although the hypercapnic ventilatory response, which reflects central chemoreceptor function, was normal during sleep in this case. One day, Ondine fell in love with a knight, Hans, who she married, thus losing her immortality. Patients with severe and extensive VA diseases more often develop recurrent cerebral infarction or coronary disease than those without.144 The presence of posterior fossa hypoperfusion may also predict poor prognosis.176. [14] Celtic languages scholar Henry Jenner has argued that the elementals grew out of the folklore that preceded them: The subdivisions and elaborations [of nature spirits] ... by Paracelsus, the Rosicrucians, and the modern theosophists are no doubt amplifications of that popular belief in the existence of a race, neither divine nor human, but very like to human beings, who existed on a "plane" different from that of humans, though occupying the same space which ... resembles the theory of these mystics in its main outlines, and was probably what suggested it to them. Ondine (mythology) synonyms, Ondine (mythology) pronunciation, Ondine (mythology) translation, English dictionary definition of Ondine (mythology).



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